Histologic examination is the microscopic analysis of a tissue sample taken by biopsy or surgical excision. It is the gold standard for many dermatologic and oncologic diagnoses, as it clarifies whether a lesion is benign, malignant, inflammatory or related to autoimmune, infectious or degenerative diseases.
Once the sample is taken, it is fixed, processed in the pathology laboratory, embedded, cut into very thin sections, stained and examined under the microscope. The pathologist issues a report describing the type of lesion, any tumour cells and their grade, and the status of the surgical margins. Histology is indicated in suspected skin cancer, atypical or doubtful lesions and after removal of moles, keratoses, cysts, lipomas and other cutaneous or subcutaneous nodules.
Treatment options
At MAVIT, every biopsy or excised specimen is sent to specialised pathology laboratories together with detailed clinical information. The histologic report is essential to confirm the clinical diagnosis, distinguish benign from malignant lesions, decide on further surgery if needed, plan additional medical treatments and define an appropriate follow-up schedule, especially in skin tumours.
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